DNA Extraction and Shotgun Metagenomics Sequencing of Fecal Samples
Contact and place of performance
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Bethesda, MD 20892
USA
This is a Notice of Intent, not a request for proposal. The National Institute of Health intends to negotiate on an other than full and open competition basis with the following vendor: Rush University Medical Center. Acquisition Description: This acquisition requested is for DNA extraction and shotgun metagenomics sequencing of fecal samples from humans (n=25) at baseline and after a ketogenic diet with/with N...
View moreAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
The National Institutes of Health intends to negotiate on an other than full and open competition basis with Rush University Medical Center to provide DNA extraction and shotgun metagenomics sequencing of fecal samples. This requirement involves processing 100 human samples and 100 mouse samples collected at baseline and after ketogenic or high-fat diets with and without NR supplementation. The resulting data will support research led by Dr. Katherine Maki to understand cross-species validation of mechanisms related to bile acid- and FXR-induced increases in ketogenesis.
Work includes DNA extraction, library preparation, and shotgun metagenomics sequencing for all 200 samples, followed by the delivery of raw data files to the government. This acquisition is categorized under NAICS 622110 for General Medical and Surgical Hospitals and PSC Q301 for MEDICAL- LABORATORY TESTING. There is no set-aside designated for this requirement, and the statutory authority for this sole source action is 41 U.S.C. 253(c)(1) as implemented by FAR 6.302-1, identifying only one responsible source capable of satisfying agency requirements.
The place of performance is Bethesda, Maryland, and the response deadline for this special notice, identified by solicitation number NOI-CC-OLAO-26-00551, is May 23, 2026. Documentation associated with this notice includes a Statement of Work and a specific quote from the intended vendor. While this is not a request for proposal, the government will consider capability statements from responsible sources submitted by the closing date to determine whether a competitive procurement should be conducted.
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